Is it possible to be starting menopause and all of the hormonal lab work turn out negative?

My mom is 49 years old and has been having sudden anxiety/depression. She describes what sounds to be like a hot flash combined with sudden anxiety and panic. She went to the MD and was tested for elevated estrogen/progesterone/luteinizing hormone, but all were within normal limits. IS it possible to be starting menopause without having elevated hormones?